R-Alpha™ is an alpha-lipoic acid supplement. Unlike many similar supplements that contain both the R- and S-isomers, R-alpha™ contains only the R-chiral-isomer of alpha-lipoic acid. Why is this important? Only the R-isomer is naturally occurring, and has been found to be a powerful antioxidant and to benefit both insulin sensitivity and carbohydrate metabolism. The S-isomer, on the other hand, is synthetically made. While it has been shown to be a fairly effective antioxidant, research has also found that it has an unhealthy effect on insulin sensitivity and carbohydrate metabolism. Thus, supplements that contain both types are actually canceling out some of their own benefits.

Why do some supplements use the S-isomer if it isn’t as effective and has negative effects? Unfortunately, R-isomer alpha-lipoic acid is substantially more expensive. Cost becomes much less of an issue, however, when the benefits are considered. In addition to its antioxidant properties and the benefits it imparts to insulin sensitivity and carbohydrate metabolism, users of R-Alpha™ also reported an increase in lean mass and decrease in fat mass, an improvement in mental outlook and increased feelings of general well-being.